Quick Answer
The best Guildrun characters depend on mode and build family. The collected material gives strong support for Nyx, Irini, Zuri, Sal, Tilly, Dragomir, Ratna, Yuuna, Niklas, Ming, Fiona, Skorn, Pimenta, Kai, Grace, and several other role pieces, but it does not prove a single permanent #1 hero. Use this page as a hub, then read the individual character guides before committing.
Best Characters by Role
For tanks, the strongest tank material points to Skorn, Pimenta, and Kai in different contexts. Skorn is the safer conventional tank answer, Pimenta has Red Rift tank/carry value, and Kai is the clearest shield-tank answer. Grace is especially important as a defensive or general-purpose Backup piece.
For Rush, Assassin, Crit, and Shard teams, Nyx, Yuuna, Dragomir, Ratna, Zuri, and Tilly all appear in useful contexts. Nyx has broad synergy with Rush, Spark, debuffs, and Assassin support. Yuuna can fit Crit, Poison, and Assassin directions, while Dragomir adds economy and kill-chain pressure.
Best Characters by Mode
Red Rift rewards stability, boss planning, and strong challenge routing. The Red Rift and comp material mentions Frost sources such as Sal, Nyx, and Aria, plus tank options like Rowan, Kai, Zuri, Skorn, and Pimenta. Do not force a hero if the run does not support its specialization.
Endless rewards repeatable or permanent scaling. Ratna, Niklas, Fiona, Tilly, Irini, Nyx, Ming, and Yuuna all have material connected to scaling, Rush, Shield, Crit, Shards, or deep-run ideas. Old deep-Endless performance can be stale after patches, so exact rankings are 待确认.
How to Use Hero Pages
Start with the problem you are solving. If you need a frontline, read best tank, Skorn/Kai/Pimenta-related notes, and Zuri or Niklas if the run supports them. If you need damage, compare Dragomir, Ratna, Yuuna, Tilly, Ming, Sal, or Irini based on the triggers and relics already present.
Hero pages should not be treated as isolated stat sheets. Guildrun heroes change meaning through ranks, specialization paths, cross-class modifiers, items, relics, and Backup effects. The best character is usually the one your current run can actually support.










